Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL4201591

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to OTR receptor (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Oxytocin receptor (CHEMBL2049)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

LIT-001, the First Nonpeptide Oxytocin Receptor Agonist that Improves Social Interaction in a Mouse Model of Autism.
Frantz MC, Pellissier LP, Pflimlin E, Loison S, Gandía J, Marsol C, Durroux T, Mouillac B, Becker JAJ, Le Merrer J, Valencia C, Villa P, Bonnet D, Hibert M.
J Med Chem (2018) 61 : 8670 -8692
PubMed 30199637 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 6.90 6.90

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL363910 1 6.90

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL363910 Ki = 125.0 nM 6.90