Assay Detail
Functional
CHEMBL4221936
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of PCSK9 expression in human HuH7 cells after overnight incubation by ELISA
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Huh-7 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Small molecule modulators of PCSK9 - A literature and patent overview.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.66 | 5.66 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4128250 | — | — | 1 | 5.66 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4128250 | — | IC50 | = | 2200.0 | nM | 5.66 |