Assay Detail
ADMET
CHEMBL4222588
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human UGT1A1 expressed in baculovirus infected insect cells using bilirubin as substrate measured after 10 mins by HPLC analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Identification of second-generation P2X3 antagonists for treatment of pain.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 6.00 | 6.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4227228 | — | — | 1 | 6.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4227228 | — | IC50 | = | 1000.0 | nM | 6.00 |