Assay Detail
Binding
CHEMBL4229728
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of 125I-C3a from human C3aR expressed in RBL-2H3 cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | RBL-2H3 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
C3a anaphylatoxin chemotactic receptor (CHEMBL4761) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Chemical Approaches to Modulating Complement-Mediated Diseases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 6.70 | 6.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL389348 | — | — | 1 | 6.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL389348 | — | IC50 | = | 200.0 | nM | 6.70 |