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Assay Detail

CHEMBL4229790

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of human thrombin
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Prothrombin (CHEMBL204)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Design of Small-Molecule Active-Site Inhibitors of the S1A Family Proteases as Procoagulant and Anticoagulant Drugs.
Fischer PM.
J Med Chem (2018) 61 : 3799 -3822
PubMed 29072911 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 7.64 7.64

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL24097 1 7.64

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL24097 Ki = 23.0 nM 7.64