Assay Detail
Functional
CHEMBL4234774
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiprotozoal activity against patient derived Trypanosoma brucei rhodesiense STIB 900 bloodstream form after 70 hrs by Alamar Blue assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Trypanosoma brucei rhodesiense |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Target
Trypanosoma brucei rhodesiense (CHEMBL612348) ↗| Type | ORGANISM |
| Organism | Trypanosoma brucei rhodesiense |
Publication
Antiprotozoal and cysteine proteases inhibitory activity of dipeptidyl enoates.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.83 | 6.03 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4251480 | — | — | 1 | 6.03 |
| CHEMBL4245127 | — | — | 1 | 5.63 |
| CHEMBL4249696 | — | — | 1 | - |
| CHEMBL4242138 | — | — | 1 | - |
| CHEMBL4244656 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4251480 | — | IC50 | = | 930.0 | nM | 6.03 |
| CHEMBL4245127 | — | IC50 | = | 2320.0 | nM | 5.63 |
| CHEMBL4249696 | — | IC50 | - | — | - | |
| CHEMBL4242138 | — | IC50 | - | — | - | |
| CHEMBL4244656 | — | IC50 | - | — | - |