Assay Detail
Functional
CHEMBL4234979
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Phototoxicity in HEK293 cells assessed as reduction in cell viability preincubated for 1 hr followed by LED light irradiation for 15 mins measured after 48 hrs by MTT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HEK293 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
The design, synthesis, and evaluation of organic dithienopyrrole-based D-π-A dyes for use as sensitizers in photodynamic therapy.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.09 | 7.37 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4237757 | — | — | 1 | 7.37 |
| CHEMBL3330737 | — | — | 1 | 6.80 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4237757 | — | IC50 | = | 43.0 | nM | 7.37 |
| CHEMBL3330737 | — | IC50 | = | 160.0 | nM | 6.80 |