Assay Detail
Binding
CHEMBL4235226
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at rat TRPV2 expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo-4-AM dye based fluorescence assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Cell Type | HEK293 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Transient receptor potential cation channel subfamily V member 2 (CHEMBL2863) ↗| Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
Publication
Iodine-mediated cyclization of cannabigerol (CBG) expands the cannabinoid biological and chemical space.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 6 | 5.21 | 5.33 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4238545 | — | — | 1 | 5.33 |
| CHEMBL4249046 | — | — | 1 | 5.24 |
| CHEMBL4242719 | — | — | 1 | 5.19 |
| CHEMBL4244422 | — | — | 1 | 5.08 |
| CHEMBL4241477 | — | — | 1 | - |
| CHEMBL4238978 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4238545 | — | EC50 | = | 4700.0 | nM | 5.33 |
| CHEMBL4249046 | — | EC50 | = | 5800.0 | nM | 5.24 |
| CHEMBL4242719 | — | EC50 | = | 6400.0 | nM | 5.19 |
| CHEMBL4244422 | — | EC50 | = | 8400.0 | nM | 5.08 |
| CHEMBL4241477 | — | EC50 | - | — | - | |
| CHEMBL4238978 | — | EC50 | - | — | - |