Assay Detail
Binding
CHEMBL4235374
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of JAK3 (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
ROCK inhibitors 3: Design, synthesis and structure-activity relationships of 7-azaindole-based Rho kinase (ROCK) inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 5.86 | 6.55 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4249925 | — | — | 1 | 6.55 |
| CHEMBL4245242 | — | — | 1 | 5.72 |
| CHEMBL4248525 | — | — | 1 | 5.32 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4249925 | — | Ki | = | 280.0 | nM | 6.55 |
| CHEMBL4245242 | — | Ki | = | 1900.0 | nM | 5.72 |
| CHEMBL4248525 | — | Ki | = | 4800.0 | nM | 5.32 |