Assay Detail
Binding
CHEMBL4236332
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Displacement of [3H]CP-55,940 from recombinant mouse Cb2 receptor expressed in HEK293 cells
17
Total Activities
17
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Cell Type | HEK293 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Oximes short-acting CB1 receptor agonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 17 | 8.46 | 10.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4239190 | — | — | 1 | 10.00 |
| CHEMBL4240671 | — | — | 1 | 9.30 |
| CHEMBL4238224 | — | — | 1 | 8.82 |
| CHEMBL4240996 | — | — | 1 | 8.80 |
| CHEMBL4246445 | — | — | 1 | 8.74 |
| CHEMBL4238778 | — | — | 1 | 8.72 |
| CHEMBL4242964 | — | — | 1 | 8.60 |
| CHEMBL4249273 | — | — | 1 | 8.59 |
| CHEMBL4245472 | — | — | 1 | 8.55 |
| CHEMBL58501 | — | — | 1 | 8.49 |
| CHEMBL4249729 | — | — | 1 | 8.43 |
| CHEMBL4237501 | — | — | 1 | 8.42 |
| CHEMBL4243768 | — | — | 1 | 8.39 |
| CHEMBL4239541 | — | — | 1 | 8.17 |
| CHEMBL464679 | — | — | 1 | 7.39 |
| CHEMBL4244186 | — | — | 1 | 7.36 |
| CHEMBL4248866 | — | — | 1 | 7.13 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4239190 | — | Ki | = | 0.1 | nM | 10.00 |
| CHEMBL4240671 | — | Ki | = | 0.5 | nM | 9.30 |
| CHEMBL4238224 | — | Ki | = | 1.5 | nM | 8.82 |
| CHEMBL4240996 | — | Ki | = | 1.6 | nM | 8.80 |
| CHEMBL4246445 | — | Ki | = | 1.8 | nM | 8.74 |
| CHEMBL4238778 | — | Ki | = | 1.9 | nM | 8.72 |
| CHEMBL4242964 | — | Ki | = | 2.5 | nM | 8.60 |
| CHEMBL4249273 | — | Ki | = | 2.6 | nM | 8.59 |
| CHEMBL4245472 | — | Ki | = | 2.8 | nM | 8.55 |
| CHEMBL58501 | — | Ki | = | 3.2 | nM | 8.49 |
| CHEMBL4249729 | — | Ki | = | 3.7 | nM | 8.43 |
| CHEMBL4237501 | — | Ki | = | 3.8 | nM | 8.42 |
| CHEMBL4243768 | — | Ki | = | 4.1 | nM | 8.39 |
| CHEMBL4239541 | — | Ki | = | 6.7 | nM | 8.17 |
| CHEMBL464679 | — | Ki | = | 40.4 | nM | 7.39 |
| CHEMBL4244186 | — | Ki | = | 43.6 | nM | 7.36 |
| CHEMBL4248866 | — | Ki | = | 74.8 | nM | 7.13 |