Assay Detail
Functional
CHEMBL4253360
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at recombinant human full length CB2 receptor expressed in HEK293 cell membranes after 2 hrs by [35S]GTP-gammaS binding assay
7
Total Activities
4
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HEK293 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Bioactive products from singlet oxygen photooxygenation of cannabinoids.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 6.90 | 9.70 |
| IC50 | 3 | 5.66 | 6.29 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL559612 | CP-55940 | — | 1 | 9.70 |
| CHEMBL4281658 | — | — | 2 | 6.59 |
| CHEMBL4291438 | — | — | 2 | 6.06 |
| CHEMBL4282822 | — | — | 2 | 5.24 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL559612 | CP-55940 | Ki | = | 0.2 | nM | 9.70 |
| CHEMBL4281658 | — | Ki | = | 259.0 | nM | 6.59 |
| CHEMBL4281658 | — | IC50 | = | 518.0 | nM | 6.29 |
| CHEMBL4291438 | — | Ki | = | 876.0 | nM | 6.06 |
| CHEMBL4291438 | — | IC50 | = | 1750.0 | nM | 5.76 |
| CHEMBL4282822 | — | Ki | = | 5700.0 | nM | 5.24 |
| CHEMBL4282822 | — | IC50 | = | 11420.0 | nM | 4.94 |