Assay Detail
Binding
CHEMBL4254594
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Binding affinity to 5-HT1A receptor (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Synthesis and antidepressant-like activity of novel aralkyl piperazine derivatives targeting SSRI/5-HT1A/5-HT7.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 8.37 | 8.83 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4204665 | — | — | 1 | 8.83 |
| CHEMBL4289361 | — | — | 1 | 8.71 |
| CHEMBL124069 | — | — | 1 | 7.58 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4204665 | — | Ki | = | 1.48 | nM | 8.83 |
| CHEMBL4289361 | — | Ki | = | 1.94 | nM | 8.71 |
| CHEMBL124069 | — | Ki | = | 26.6 | nM | 7.58 |