Assay Detail
Functional
CHEMBL4254800
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at 5HT1A receptor (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Synthesis and biological evaluation of a series of multi-target N-substituted cyclic imide derivatives with potential antipsychotic effect.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 8.15 | 8.24 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL274047 | TANDOSPIRONE | 2.0 | 1 | 8.24 |
| CHEMBL49 | BUSPIRONE | 4.0 | 1 | 8.05 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL274047 | TANDOSPIRONE | Ki | = | 5.8 | nM | 8.24 |
| CHEMBL49 | BUSPIRONE | Ki | = | 8.9 | nM | 8.05 |