Assay Detail
Binding
CHEMBL4257133
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of NHE3 (unknown origin)
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Publication
Nhe3-binding compounds and methods for inhibiting phosphate transport
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.64 | 7.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3897683 | — | — | 1 | 7.70 |
| CHEMBL3900457 | — | — | 1 | 5.88 |
| CHEMBL3900790 | — | — | 1 | 4.96 |
| CHEMBL64360 | ENIPORIDE | 2.0 | 1 | 4.00 |
| CHEMBL51879 | — | — | 1 | - |
| CHEMBL3974005 | — | — | 1 | - |
| CHEMBL436559 | CARIPORIDE | 2.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3897683 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL3900457 | — | IC50 | = | 1320.0 | nM | 5.88 |
| CHEMBL3900790 | — | IC50 | = | 11000.0 | nM | 4.96 |
| CHEMBL64360 | ENIPORIDE | IC50 | = | 100000.0 | nM | 4.00 |
| CHEMBL51879 | — | IC50 | > | 30000.0 | nM | - |
| CHEMBL3974005 | — | IC50 | > | 30000.0 | nM | - |
| CHEMBL436559 | CARIPORIDE | IC50 | >= | 1000.0 | nM | - |