Assay Detail
Functional
CHEMBL4263293
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Antiparasitic activity against Trichomonas vaginalis assessed as parasite growth inhibition after 24 hrs by hemacytometer
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Trichomonas vaginalis |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Design, Synthesis and Preliminary Antimicrobial Evaluation of <i>N</i>-Alkyl Chain Tethered C-5 Functionalized Bis-Isatins.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.18 | 6.14 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL137 | METRONIDAZOLE | 4.0 | 1 | 6.14 |
| CHEMBL4290102 | — | — | 1 | 5.43 |
| CHEMBL4289798 | — | — | 1 | 4.90 |
| CHEMBL4276974 | — | — | 1 | 4.82 |
| CHEMBL4279419 | — | — | 1 | 4.60 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL137 | METRONIDAZOLE | IC50 | = | 720.0 | nM | 6.14 |
| CHEMBL4290102 | — | IC50 | = | 3720.0 | nM | 5.43 |
| CHEMBL4289798 | — | IC50 | = | 12500.0 | nM | 4.90 |
| CHEMBL4276974 | — | IC50 | = | 15000.0 | nM | 4.82 |
| CHEMBL4279419 | — | IC50 | = | 25000.0 | nM | 4.60 |