Assay Detail
Binding
CHEMBL4265047
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of HFIP-pretreated amyloid beta (1 to 42) (unknown origin) self-induced aggregation after 24 hrs by thioflavin-T fluorescence assay
14
Total Activities
14
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Publication
Resveratrol-maltol hybrids as multi-target-directed agents for Alzheimer's disease.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 14 | 4.96 | 5.23 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4294375 | — | — | 1 | 5.23 |
| CHEMBL4287929 | — | — | 1 | 5.14 |
| CHEMBL4286002 | — | — | 1 | 5.10 |
| CHEMBL4284208 | — | — | 1 | 5.08 |
| CHEMBL165 | RESVERATROL | 3.0 | 1 | 4.92 |
| CHEMBL4282190 | — | — | 1 | 4.75 |
| CHEMBL4294830 | — | — | 1 | 4.75 |
| CHEMBL140 | CURCUMIN | 3.0 | 1 | 4.73 |
| CHEMBL2283266 | — | — | 1 | - |
| CHEMBL4292488 | — | — | 1 | - |
| CHEMBL4284114 | — | — | 1 | - |
| CHEMBL4286108 | — | — | 1 | - |
| CHEMBL4289536 | — | — | 1 | - |
| CHEMBL153 | TROLOX | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4294375 | — | IC50 | = | 5920.0 | nM | 5.23 |
| CHEMBL4287929 | — | IC50 | = | 7200.0 | nM | 5.14 |
| CHEMBL4286002 | — | IC50 | = | 7930.0 | nM | 5.10 |
| CHEMBL4284208 | — | IC50 | = | 8290.0 | nM | 5.08 |
| CHEMBL165 | RESVERATROL | IC50 | = | 11890.0 | nM | 4.92 |
| CHEMBL4282190 | — | IC50 | = | 17680.0 | nM | 4.75 |
| CHEMBL4294830 | — | IC50 | = | 17950.0 | nM | 4.75 |
| CHEMBL140 | CURCUMIN | IC50 | = | 18730.0 | nM | 4.73 |
| CHEMBL2283266 | — | IC50 | - | — | - | |
| CHEMBL4292488 | — | IC50 | - | — | - | |
| CHEMBL4284114 | — | IC50 | - | — | - | |
| CHEMBL4286108 | — | IC50 | - | — | - | |
| CHEMBL4289536 | — | IC50 | - | — | - | |
| CHEMBL153 | TROLOX | IC50 | - | — | - |