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Assay Detail

CHEMBL4271172

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity in human HuH7 cells assessed as reduction in cell viability incubated for 72 hrs by cell-titer Glo asay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type Huh-7
Confidence 1 — Organism
Curated By Intermediate

Target

Huh-7 (CHEMBL614039)
Type CELL-LINE
Organism Homo sapiens

Publication

Oleanane-, ursane-, and quinone methide friedelane-type triterpenoid derivatives: Recent advances in cancer treatment.
Salvador JAR, Leal AS, Valdeira AS, Gonçalves BMF, Alho DPS, Figueiredo SAC, Silvestre SM, Mendes VIS.
Eur J Med Chem (2017) 142 : 95 -130
PubMed 28754470 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.83 5.98

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4288196 1 5.98
CHEMBL1170915 1 5.67

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4288196 IC50 = 1040.0 nM 5.98
CHEMBL1170915 IC50 = 2150.0 nM 5.67