Assay Detail
ADMET
CHEMBL4272594
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Cytotoxicity against human FHC cells
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | FHC |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Copper(I) oxide nanoparticles catalyzed click chemistry based synthesis of melampomagnolide B-triazole conjugates and their anti-cancer activities.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 6.16 | 7.24 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL359744 | DOXORUBICIN HYDROCHLORIDE | 4.0 | 1 | 7.24 |
| CHEMBL4278178 | — | — | 1 | 6.20 |
| CHEMBL4294165 | — | — | 1 | 6.17 |
| CHEMBL4282880 | — | — | 1 | 5.99 |
| CHEMBL4298697 | — | — | 1 | 5.81 |
| CHEMBL563939 | — | — | 1 | 5.55 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL359744 | DOXORUBICIN HYDROCHLORIDE | IC50 | = | 57.0 | nM | 7.24 |
| CHEMBL4278178 | — | IC50 | = | 630.0 | nM | 6.20 |
| CHEMBL4294165 | — | IC50 | = | 670.0 | nM | 6.17 |
| CHEMBL4282880 | — | IC50 | = | 1020.0 | nM | 5.99 |
| CHEMBL4298697 | — | IC50 | = | 1560.0 | nM | 5.81 |
| CHEMBL563939 | — | IC50 | = | 2810.0 | nM | 5.55 |