Assay Detail
ADMET
CHEMBL4272596
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Cytotoxicity against mouse 3T3 cells
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Mus musculus |
| Cell Type | NIH3T3 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Copper(I) oxide nanoparticles catalyzed click chemistry based synthesis of melampomagnolide B-triazole conjugates and their anti-cancer activities.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.55 | 6.26 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL359744 | DOXORUBICIN HYDROCHLORIDE | 4.0 | 1 | 6.26 |
| CHEMBL4294165 | — | — | 1 | 5.74 |
| CHEMBL4278178 | — | — | 1 | 5.64 |
| CHEMBL4282880 | — | — | 1 | 5.46 |
| CHEMBL4298697 | — | — | 1 | 5.27 |
| CHEMBL563939 | — | — | 1 | 4.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL359744 | DOXORUBICIN HYDROCHLORIDE | IC50 | = | 550.0 | nM | 6.26 |
| CHEMBL4294165 | — | IC50 | = | 1810.0 | nM | 5.74 |
| CHEMBL4278178 | — | IC50 | = | 2270.0 | nM | 5.64 |
| CHEMBL4282880 | — | IC50 | = | 3450.0 | nM | 5.46 |
| CHEMBL4298697 | — | IC50 | = | 5350.0 | nM | 5.27 |
| CHEMBL563939 | — | IC50 | = | 12000.0 | nM | 4.92 |