Assay Detail
Functional
CHEMBL4275086
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against human CNE1 cells after 72 hrs by MTT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | CNE |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Design, synthesis, biological evaluation and structure-activity relationship of sophoridine derivatives bearing pyrrole or indole scaffold as potential antitumor agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.10 | 6.47 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL65 | CAMPTOTHECIN | -1.0 | 1 | 6.47 |
| CHEMBL4288799 | — | — | 1 | 5.72 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL65 | CAMPTOTHECIN | IC50 | = | 340.0 | nM | 6.47 |
| CHEMBL4288799 | — | IC50 | = | 1890.0 | nM | 5.72 |