Assay Detail
Binding
CHEMBL4276647
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Displacement of [125I]OH-Phpa-LVA from human V1A receptor expressed in CHO cells after 4 hrs by gamma counter analysis
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | CHO |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Receptor-Ligand Interaction Measured by Inductively Coupled Plasma Mass Spectrometry and Selenium Labeling.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 8 | 8.31 | 9.28 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL419667 | RELCOVAPTAN | 2.0 | 1 | 9.28 |
| CHEMBL4294901 | — | — | 1 | 9.15 |
| CHEMBL4281963 | — | — | 1 | 9.10 |
| CHEMBL4289837 | — | — | 1 | 9.05 |
| CHEMBL4278500 | — | — | 1 | 9.05 |
| CHEMBL562961 | — | — | 1 | 8.42 |
| CHEMBL4283439 | — | — | 1 | 6.52 |
| CHEMBL4286989 | — | — | 1 | 5.89 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL419667 | RELCOVAPTAN | Ki | = | 0.53 | nM | 9.28 |
| CHEMBL4294901 | — | Ki | = | 0.7 | nM | 9.15 |
| CHEMBL4281963 | — | Ki | = | 0.8 | nM | 9.10 |
| CHEMBL4289837 | — | Ki | = | 0.9 | nM | 9.05 |
| CHEMBL4278500 | — | Ki | = | 0.9 | nM | 9.05 |
| CHEMBL562961 | — | Ki | = | 3.8 | nM | 8.42 |
| CHEMBL4283439 | — | Ki | = | 304.0 | nM | 6.52 |
| CHEMBL4286989 | — | Ki | = | 1280.0 | nM | 5.89 |