Assay Detail
Binding
CHEMBL4276648
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Displacement of [Se-Se]-AVP from human V1A receptor expressed in CHO cells after 4 hrs by RP-LC-ICPMS analysis
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | CHO |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Receptor-Ligand Interaction Measured by Inductively Coupled Plasma Mass Spectrometry and Selenium Labeling.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 8.49 | 9.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4281963 | — | — | 1 | 9.70 |
| CHEMBL4289837 | — | — | 1 | 9.40 |
| CHEMBL419667 | RELCOVAPTAN | 2.0 | 1 | 9.05 |
| CHEMBL4294901 | — | — | 1 | 8.77 |
| CHEMBL4283439 | — | — | 1 | 5.53 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4281963 | — | Ki | = | 0.2 | nM | 9.70 |
| CHEMBL4289837 | — | Ki | = | 0.4 | nM | 9.40 |
| CHEMBL419667 | RELCOVAPTAN | Ki | = | 0.9 | nM | 9.05 |
| CHEMBL4294901 | — | Ki | = | 1.7 | nM | 8.77 |
| CHEMBL4283439 | — | Ki | = | 2949.0 | nM | 5.53 |