Assay Detail
Binding
CHEMBL4303096
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Activity of compound against Alpha 2B (ADRA2B) adrenergic receptor by displacement of [3H]-rauwolscine
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
A SARS-CoV-2 protein interaction map reveals targets for drug repurposing
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 4.94 | 6.32 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1626 | CLEMASTINE | 4.0 | 1 | 6.32 |
| CHEMBL53325 | — | — | 1 | 5.03 |
| CHEMBL4088272 | — | — | 1 | 4.69 |
| CHEMBL76 | CHLOROQUINE | 4.0 | 1 | 4.50 |
| CHEMBL1535 | HYDROXYCHLOROQUINE | 4.0 | 1 | 4.14 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1626 | CLEMASTINE | Ki | = | 478.63 | nM | 6.32 |
| CHEMBL53325 | — | Ki | = | 9332.54 | nM | 5.03 |
| CHEMBL4088272 | — | Ki | = | 20417.38 | nM | 4.69 |
| CHEMBL76 | CHLOROQUINE | Ki | = | 31622.78 | nM | 4.50 |
| CHEMBL1535 | HYDROXYCHLOROQUINE | Ki | = | 72443.6 | nM | 4.14 |