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Assay Detail

CHEMBL4305663

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against mouse 3T3 cells
21
Total Activities
21
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Cell Type NIH3T3
Confidence 1 — Organism
Curated By Autocuration

Target

NIH3T3 (CHEMBL614822)
Type CELL-LINE
Organism Mus musculus

Publication

Synthetic heterocyclic candidates as promising α-glucosidase inhibitors: An overview.
Dhameja M, Gupta P.
Eur J Med Chem (2019) 176 : 343 -377
PubMed 31112894 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 21 6.21 6.21

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4468361 1 6.21
CHEMBL4447393 1 6.21
CHEMBL4475174 1 6.21
CHEMBL4593619 1 6.21
CHEMBL4435572 1 6.21
CHEMBL4539228 1 6.21
CHEMBL4455934 1 6.21
CHEMBL4559950 1 6.21
CHEMBL4456736 1 6.21
CHEMBL4443159 1 6.21
CHEMBL4513726 1 6.21
CHEMBL4460638 1 6.21
CHEMBL4548709 1 6.21
CHEMBL4589941 1 6.21
CHEMBL4567497 1 6.21
CHEMBL4462006 1 6.21
CHEMBL4550154 1 6.21
CHEMBL4434647 1 6.21
CHEMBL4465892 1 6.21
CHEMBL4545512 1 6.21
CHEMBL4593214 1 6.21

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4468361 IC50 = 610.0 nM 6.21
CHEMBL4447393 IC50 = 610.0 nM 6.21
CHEMBL4475174 IC50 = 610.0 nM 6.21
CHEMBL4593619 IC50 = 610.0 nM 6.21
CHEMBL4435572 IC50 = 610.0 nM 6.21
CHEMBL4539228 IC50 = 610.0 nM 6.21
CHEMBL4455934 IC50 = 610.0 nM 6.21
CHEMBL4559950 IC50 = 610.0 nM 6.21
CHEMBL4456736 IC50 = 610.0 nM 6.21
CHEMBL4443159 IC50 = 610.0 nM 6.21
CHEMBL4513726 IC50 = 610.0 nM 6.21
CHEMBL4460638 IC50 = 610.0 nM 6.21
CHEMBL4548709 IC50 = 610.0 nM 6.21
CHEMBL4589941 IC50 = 610.0 nM 6.21
CHEMBL4567497 IC50 = 610.0 nM 6.21
CHEMBL4462006 IC50 = 610.0 nM 6.21
CHEMBL4550154 IC50 = 610.0 nM 6.21
CHEMBL4434647 IC50 = 610.0 nM 6.21
CHEMBL4465892 IC50 = 610.0 nM 6.21
CHEMBL4545512 IC50 = 610.0 nM 6.21
CHEMBL4593214 IC50 = 610.0 nM 6.21