Assay Detail
Functional
CHEMBL4307229
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Decrease in UPA expression in human HT1080 cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HT-1080 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Recent advances of analogues of curcumin for treatment of cancer.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.09 | 5.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL105350 | BISDEMETHOXYCURCUMIN | — | 1 | 5.16 |
| CHEMBL105360 | — | — | 1 | 5.12 |
| CHEMBL140 | CURCUMIN | 3.0 | 1 | 5.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL105350 | BISDEMETHOXYCURCUMIN | IC50 | = | 7000.0 | nM | 5.16 |
| CHEMBL105360 | — | IC50 | = | 7500.0 | nM | 5.12 |
| CHEMBL140 | CURCUMIN | IC50 | = | 10000.0 | nM | 5.00 |