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Assay Detail

CHEMBL4308987

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of Vps34 in human HeLa cells expressing GFP-FYVE
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Cell Type HeLa
Confidence 9 — Direct single protein target
Curated By Autocuration

Publication

Design of Small Molecule Autophagy Modulators: A Promising Druggable Strategy.
He S, Li Q, Jiang X, Lu X, Feng F, Qu W, Chen Y, Sun H.
J Med Chem (2018) 61 : 4656 -4687
PubMed 29211480 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.57 7.57

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3622372 1 7.57

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3622372 IC50 = 27.0 nM 7.57