Assay Detail
Functional
CHEMBL4309337
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against human TF1 cells transfected with IDH1 R132H mutant
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | TF-1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Inhibitors of Mutant Isocitrate Dehydrogenases 1 and 2 (mIDH1/2): An Update and Perspective.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 8.76 | 8.76 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4444886 | — | — | 1 | 8.76 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4444886 | — | IC50 | = | 1.75 | nM | 8.76 |