Assay Detail
Binding
CHEMBL4311137
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Inhibition of MPO (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
The development of myeloperoxidase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.29 | 6.38 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1043 | DAPSONE | 4.0 | 1 | 6.38 |
| CHEMBL4297594 | VERDIPERSTAT | 3.0 | 1 | 6.20 |
| CHEMBL25 | ASPIRIN | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1043 | DAPSONE | IC50 | = | 420.0 | nM | 6.38 |
| CHEMBL4297594 | VERDIPERSTAT | IC50 | = | 630.0 | nM | 6.20 |
| CHEMBL25 | ASPIRIN | IC50 | = | 200000.0 | nM | - |