Assay Detail
Functional
CHEMBL4316334
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against human MGC803 cells measured after 48 hrs by CCK8 assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MGC-803 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Discovery of candesartan cilexetic as a novel neddylation inhibitor for suppressing tumor growth.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.24 | 4.24 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1014 | CANDESARTAN CILEXETIL | 4.0 | 1 | 4.24 |
| CHEMBL1231160 | PEVONEDISTAT | 3.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1014 | CANDESARTAN CILEXETIL | IC50 | = | 57140.0 | nM | 4.24 |
| CHEMBL1231160 | PEVONEDISTAT | IC50 | > | 10000.0 | nM | - |