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Assay Detail

CHEMBL4321981

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to N-terminal sonic hedgehog (unknown origin) by surface plasmon resonance analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Sonic hedgehog protein (CHEMBL5602)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Inhibiting Hedgehog: An Update on Pharmacological Compounds and Targeting Strategies.
Galperin I, Dempwolff L, Diederich WE, Lauth M.
J Med Chem (2019) 62 : 8392 -8411
PubMed 30986059 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 5.51 5.51

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL473392 ROBOTNIKININ 1 5.51

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL473392 ROBOTNIKININ Kd = 3100.0 nM 5.51