Assay Detail
Binding
CHEMBL4322117
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Inhibition of mouse brain AChE
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Rational Design of Multitarget-Directed Ligands: Strategies and Emerging Paradigms.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 6.95 | 8.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL497071 | — | — | 1 | 8.00 |
| CHEMBL197696 | — | — | 1 | 7.85 |
| CHEMBL194372 | — | — | 1 | 7.00 |
| CHEMBL636 | RIVASTIGMINE | 4.0 | 1 | 4.96 |
| CHEMBL41 | FLUOXETINE | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL497071 | — | IC50 | = | 10.0 | nM | 8.00 |
| CHEMBL197696 | — | IC50 | = | 14.0 | nM | 7.85 |
| CHEMBL194372 | — | IC50 | = | 101.0 | nM | 7.00 |
| CHEMBL636 | RIVASTIGMINE | IC50 | = | 11000.0 | nM | 4.96 |
| CHEMBL41 | FLUOXETINE | IC50 | > | 10000.0 | nM | - |