Assay Detail
Binding
CHEMBL4322137
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of glucocorticoid receptor (unknown origin)
3
Total Activities
3
Compounds Tested
3
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Why Some Targets Benefit from beyond Rule of Five Drugs.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 1 | 7.72 | 7.72 |
| IC50 | 1 | 8.20 | 8.20 |
| Ki | 1 | 9.15 | 9.15 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1161 | MOMETASONE FUROATE | 4.0 | 1 | 9.15 |
| CHEMBL1233786 | — | — | 1 | 8.20 |
| CHEMBL384467 | DEXAMETHASONE | 4.0 | 1 | 7.72 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1161 | MOMETASONE FUROATE | Ki | = | 0.7 | nM | 9.15 |
| CHEMBL1233786 | — | IC50 | = | 6.3 | nM | 8.20 |
| CHEMBL384467 | DEXAMETHASONE | Kd | = | 19.0 | nM | 7.72 |