Assay Detail
Binding
CHEMBL4322157
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human TASK3 expressed in Xenopus oocytes by whole cell voltage clamp assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Potassium channel subfamily K member 9 (CHEMBL2321614) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
TASK Channels Pharmacology: New Challenges in Drug Design.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 6.38 | 6.61 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2324344 | — | — | 1 | 6.61 |
| CHEMBL148342 | — | — | 1 | 6.50 |
| CHEMBL4592278 | — | — | 1 | 6.02 |
| CHEMBL4521731 | — | — | 1 | - |
| CHEMBL4466298 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2324344 | — | IC50 | = | 243.0 | nM | 6.61 |
| CHEMBL148342 | — | IC50 | = | 318.0 | nM | 6.50 |
| CHEMBL4592278 | — | IC50 | = | 950.0 | nM | 6.02 |
| CHEMBL4521731 | — | IC50 | = | 189200.0 | nM | - |
| CHEMBL4466298 | — | IC50 | = | 268100.0 | nM | - |