Assay Detail
Binding
CHEMBL4324449
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Agonist activity at melatonin receptor in Xenopus laevis melanophores assessed as induction of pigment aggregation response by measuring changes in light absorbance
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Xenopus laevis |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Indole-based melatonin analogues: Synthetic approaches and biological activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 9.85 | 10.75 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4568545 | — | — | 1 | 10.75 |
| CHEMBL45 | MELATONIN | 4.0 | 1 | 10.70 |
| CHEMBL4466258 | — | — | 1 | 8.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4568545 | — | EC50 | = | 0.01778 | nM | 10.75 |
| CHEMBL45 | MELATONIN | EC50 | = | 0.01995 | nM | 10.70 |
| CHEMBL4466258 | — | EC50 | = | 7.943 | nM | 8.10 |