Assay Detail
Functional
CHEMBL4325460
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Antiproliferative activity against human Kasumi-1 cells measured after 3 days by celltiter-glo luminescence assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Kasumi 1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Discovery of Highly Potent, Selective, and Orally Efficacious p300/CBP Histone Acetyltransferases Inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.81 | 7.39 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4587968 | — | — | 1 | 7.39 |
| CHEMBL4282264 | A-485 | — | 1 | 6.22 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4587968 | — | IC50 | = | 40.5 | nM | 7.39 |
| CHEMBL4282264 | A-485 | IC50 | = | 607.9 | nM | 6.22 |