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Assay Detail

CHEMBL4326976

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to Pseudomonas aeruginosa LecB
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Pseudomonas aeruginosa
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Fucose-binding lectin PA-IIL (CHEMBL4523938)
Type SINGLE PROTEIN
Organism Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM14847 / LMG 12228 / 1C / PRS 101 / PAO1)

Publication

Synthetic small molecules as anti-biofilm agents in the struggle against antibiotic resistance.
Parrino B, Schillaci D, Carnevale I, Giovannetti E, Diana P, Cirrincione G, Cascioferro S.
Eur J Med Chem (2019) 161 : 154 -178
PubMed 30347328 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 5.11 5.11

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4450053 1 5.11

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4450053 Kd = 7700.0 nM 5.11