Assay Detail
Binding
CHEMBL4327339
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human serum BuChE using butyrylthiocholine iodide as substrate by Ellman's method
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Investigating alkyl nitrates as nitric oxide releasing precursors of multitarget acetylcholinesterase-monoamine oxidase B inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.12 | 6.13 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4470448 | — | — | 1 | 6.13 |
| CHEMBL4578377 | — | — | 1 | 6.10 |
| CHEMBL4450045 | — | — | 1 | - |
| CHEMBL4459482 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4470448 | — | IC50 | = | 740.0 | nM | 6.13 |
| CHEMBL4578377 | — | IC50 | = | 800.0 | nM | 6.10 |
| CHEMBL4450045 | — | IC50 | - | — | - | |
| CHEMBL4459482 | — | IC50 | - | — | - |