Assay Detail
Binding
CHEMBL4329360
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of recombinant N-terminal GST-tagged human HDAC7 (518 to 991 residues) expressed in Baculovirus infected insect cells using Boc-K(Ac)-AMC as substrate by fluorimetric assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Highly fluorescent and HDAC6 selective scriptaid analogues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.27 | 5.50 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4532304 | — | — | 1 | 5.50 |
| CHEMBL4475116 | — | — | 1 | 5.03 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4532304 | — | IC50 | = | 3200.0 | nM | 5.50 |
| CHEMBL4475116 | — | IC50 | = | 9400.0 | nM | 5.03 |