Assay Detail
Binding
CHEMBL4330498
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Inhibition of human SSTR4 by radioligand binding assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Ligand design for somatostatin receptor isoforms 4 and 5.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 8.07 | 8.75 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1823872 | SOMATOSTATIN | 3.0 | 1 | 8.75 |
| CHEMBL227212 | — | — | 1 | 8.48 |
| CHEMBL4459308 | — | — | 1 | 6.99 |
| CHEMBL1680 | OCTREOTIDE | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1823872 | SOMATOSTATIN | IC50 | = | 1.77 | nM | 8.75 |
| CHEMBL227212 | — | IC50 | = | 3.3 | nM | 8.48 |
| CHEMBL4459308 | — | IC50 | = | 103.0 | nM | 6.99 |
| CHEMBL1680 | OCTREOTIDE | IC50 | > | 1000.0 | nM | - |