Assay Detail
Binding
CHEMBL4332327
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Activation of firefly luciferase activity expressed in HEK293T cells after 6 hrs by luminescence assay
2
Total Activities
2
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Photinus pyralis |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Discovery of an isocoumarin analogue that modulates neuronal functions via neurotrophin receptor TrkB.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 8.00 | 8.00 |
| Activity | 1 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL279115 | PHORBOL MYRISTATE ACETATE | 2.0 | 1 | 8.00 |
| CHEMBL4471556 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL279115 | PHORBOL MYRISTATE ACETATE | EC50 | = | 10.0 | nM | 8.00 |
| CHEMBL4471556 | — | Activity | - | — | - |