Assay Detail
Functional
CHEMBL4333749
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antibacterial activity against Escherichia coli ATCC 8739 after 17 hrs by resazurin dye based fluorimetric assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Escherichia coli |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis and antimicrobial activities of N<sup>6</sup>-hydroxyagelasine analogs and revision of the structure of ageloximes.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.24 | 6.24 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1200699 | DOXYCYCLINE | 4.0 | 1 | 6.24 |
| CHEMBL4443174 | — | — | 1 | - |
| CHEMBL4592498 | — | — | 1 | - |
| CHEMBL4469221 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1200699 | DOXYCYCLINE | IC50 | = | 580.0 | nM | 6.24 |
| CHEMBL4443174 | — | IC50 | > | 64000.0 | nM | - |
| CHEMBL4592498 | — | IC50 | > | 64000.0 | nM | - |
| CHEMBL4469221 | — | IC50 | > | 64000.0 | nM | - |