Assay Detail
Binding
CHEMBL4334031
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to PPARgamma (unknown origin) by TR-FRET assay
8
Total Activities
5
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Peroxisome proliferator-activated receptor gamma (CHEMBL235) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Adiponectin-Secretion-Promoting Phenylethylchromones from the Agarwood of Aquilaria malaccensis.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 5.45 | 7.21 |
| Activity | 3 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL595 | PIOGLITAZONE | 4.0 | 1 | 7.21 |
| CHEMBL472 | GLYBURIDE | 4.0 | 1 | 6.18 |
| CHEMBL4555353 | — | — | 2 | 4.83 |
| CHEMBL4453254 | — | — | 2 | 4.74 |
| CHEMBL481060 | FLIDERSIACHROMONE | — | 2 | 4.27 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL595 | PIOGLITAZONE | Ki | = | 62.0 | nM | 7.21 |
| CHEMBL472 | GLYBURIDE | Ki | = | 660.0 | nM | 6.18 |
| CHEMBL4555353 | — | Ki | = | 14900.0 | nM | 4.83 |
| CHEMBL4453254 | — | Ki | = | 18100.0 | nM | 4.74 |
| CHEMBL481060 | FLIDERSIACHROMONE | Ki | = | 54000.0 | nM | 4.27 |
| CHEMBL481060 | FLIDERSIACHROMONE | Activity | - | — | - | |
| CHEMBL4453254 | — | Activity | - | — | - | |
| CHEMBL4555353 | — | Activity | - | — | - |