Assay Detail
Functional
CHEMBL4334323
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Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HCT-116 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Advance of Seriniquinone Analogues as Melanoma Agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 5.79 | 6.32 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | 4.0 | 1 | 6.32 |
| CHEMBL4576074 | — | — | 1 | 6.27 |
| CHEMBL4476574 | — | — | 1 | 6.12 |
| CHEMBL4438542 | — | — | 1 | 5.89 |
| CHEMBL4450400 | — | — | 1 | 5.84 |
| CHEMBL4437459 | — | — | 1 | 5.39 |
| CHEMBL4554800 | — | — | 1 | 5.37 |
| CHEMBL4474312 | — | — | 1 | 5.09 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | IC50 | = | 480.0 | nM | 6.32 |
| CHEMBL4576074 | — | IC50 | = | 540.0 | nM | 6.27 |
| CHEMBL4476574 | — | IC50 | = | 750.0 | nM | 6.12 |
| CHEMBL4438542 | — | IC50 | = | 1290.0 | nM | 5.89 |
| CHEMBL4450400 | — | IC50 | = | 1450.0 | nM | 5.84 |
| CHEMBL4437459 | — | IC50 | = | 4080.0 | nM | 5.39 |
| CHEMBL4554800 | — | IC50 | = | 4240.0 | nM | 5.37 |
| CHEMBL4474312 | — | IC50 | = | 8160.0 | nM | 5.09 |