Assay Detail
Binding
CHEMBL4334760
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Reversible inhibition of Escherichia coli dihydrodipicolinate synthase using ASA as substrate
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Escherichia coli |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
4-hydroxy-tetrahydrodipicolinate synthase (CHEMBL4083) ↗| Type | SINGLE PROTEIN |
| Organism | Escherichia coli K-12 |
Publication
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 4.05 | 4.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL274323 | ASPARTIC ACID | 3.0 | 1 | 4.05 |
| CHEMBL1233424 | HOMOSERINE LACTONE | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL274323 | ASPARTIC ACID | Ki | = | 90000.0 | nM | 4.05 |
| CHEMBL1233424 | HOMOSERINE LACTONE | Ki | = | 12000000.0 | nM | - |