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Assay Detail

CHEMBL4334860

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Displacement of [125I]iodosupride from human recombinant dopamine D3 receptor expressed in CHO cells incubated for 30 mins by competitive radioligand binding analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Cell Type CHO
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

D(3) dopamine receptor (CHEMBL234)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Medchemcomm (2019) 10 : 1926 -1929
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 7.17 7.17

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL279085 TALIPEXOLE 2.0 1 7.17

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL279085 TALIPEXOLE Ki = 67.61 nM 7.17