Assay Detail
Binding
CHEMBL4337201
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Inhibition of human AChE
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Multi-target-directed-ligands acting as enzyme inhibitors and receptor ligands.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 5.74 | 7.47 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3323035 | — | — | 1 | 7.47 |
| CHEMBL4173258 | — | — | 1 | 6.28 |
| CHEMBL1929421 | — | — | 1 | 6.09 |
| CHEMBL4566976 | — | — | 1 | 5.80 |
| CHEMBL4591636 | — | — | 1 | 5.62 |
| CHEMBL4545210 | — | — | 1 | 5.30 |
| CHEMBL3323053 | — | — | 1 | 5.27 |
| CHEMBL14638 | CIPROXIFAN | — | 1 | 4.07 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3323035 | — | IC50 | = | 33.9 | nM | 7.47 |
| CHEMBL4173258 | — | IC50 | = | 530.0 | nM | 6.28 |
| CHEMBL1929421 | — | IC50 | = | 810.0 | nM | 6.09 |
| CHEMBL4566976 | — | IC50 | = | 1600.0 | nM | 5.80 |
| CHEMBL4591636 | — | IC50 | = | 2400.0 | nM | 5.62 |
| CHEMBL4545210 | — | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL3323053 | — | IC50 | = | 5400.0 | nM | 5.27 |
| CHEMBL14638 | CIPROXIFAN | IC50 | = | 86100.0 | nM | 4.07 |