Assay Detail
Functional
CHEMBL4338386
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antitrypanosomal activity against blood stage form of Trypanosoma brucei brucei 449 incubated for 24 hrs by ATPlite assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Trypanosoma brucei brucei |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Optimization Strategy of Novel Peptide-Based Michael Acceptors for the Treatment of Human African Trypanosomiasis.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 6 | 5.62 | 6.26 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4438444 | — | — | 1 | 6.26 |
| CHEMBL4566436 | — | — | 1 | 6.13 |
| CHEMBL4436812 | — | — | 1 | 5.40 |
| CHEMBL4584291 | — | — | 1 | 5.32 |
| CHEMBL4437914 | — | — | 1 | 5.30 |
| CHEMBL4475066 | — | — | 1 | 5.29 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4438444 | — | EC50 | = | 550.0 | nM | 6.26 |
| CHEMBL4566436 | — | EC50 | = | 740.0 | nM | 6.13 |
| CHEMBL4436812 | — | EC50 | = | 4000.0 | nM | 5.40 |
| CHEMBL4584291 | — | EC50 | = | 4800.0 | nM | 5.32 |
| CHEMBL4437914 | — | EC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL4475066 | — | EC50 | = | 5100.0 | nM | 5.29 |