Assay Detail
Functional
CHEMBL4338648
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Cytotoxicity against human A431 cells measured after 72 hrs by Celltiter-Glo assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | A-431 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Cytotoxic p-Terphenyls from a Marine-Derived Nocardiopsis Species.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 6.07 | 6.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | 4.0 | 1 | 6.80 |
| CHEMBL4441293 | — | — | 1 | 5.34 |
| CHEMBL4544616 | — | — | 1 | - |
| CHEMBL2289484 | — | — | 1 | - |
| CHEMBL4472763 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | IC50 | = | 160.0 | nM | 6.80 |
| CHEMBL4441293 | — | IC50 | = | 4600.0 | nM | 5.34 |
| CHEMBL4544616 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL2289484 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL4472763 | — | IC50 | > | 100000.0 | nM | - |