Assay Detail
Binding
CHEMBL4338741
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H] UR-MK300 from human neurotensin receptor 2 in HEK293 cells homogenate incubated in dark after 30 mins by liquid scintillation counter analysis
9
Total Activities
9
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | HEK293 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Fluorescence Labeling of Neurotensin(8-13) via Arginine Residues Gives Molecular Tools with High Receptor Affinity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 8.68 | 9.13 |
| pKi | 3 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL415788 | — | — | 1 | 9.13 |
| CHEMBL4534768 | — | — | 1 | 9.02 |
| CHEMBL4564746 | — | — | 1 | 8.92 |
| CHEMBL4537266 | — | — | 1 | 8.46 |
| CHEMBL4457798 | — | — | 1 | 8.40 |
| CHEMBL4592541 | — | — | 1 | 8.14 |
| CHEMBL4463399 | — | — | 1 | - |
| CHEMBL4584647 | — | — | 1 | - |
| CHEMBL4566971 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL415788 | — | Ki | = | 0.7413 | nM | 9.13 |
| CHEMBL4534768 | — | Ki | = | 0.955 | nM | 9.02 |
| CHEMBL4564746 | — | Ki | = | 1.202 | nM | 8.92 |
| CHEMBL4537266 | — | Ki | = | 3.467 | nM | 8.46 |
| CHEMBL4457798 | — | Ki | = | 3.981 | nM | 8.40 |
| CHEMBL4592541 | — | Ki | = | 7.244 | nM | 8.14 |
| CHEMBL4463399 | — | pKi | - | — | - | |
| CHEMBL4584647 | — | pKi | - | — | - | |
| CHEMBL4566971 | — | pKi | - | — | - |