Assay Detail
Functional
CHEMBL4340463
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Antimicrobial activity against Escherichia coli ATCC 35218 assessed as inhibition of microbial growth by CLSI based method
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Escherichia coli |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Anthraquinone-Based Specialized Metabolites from Rhizomes of <i>Bulbine natalensis</i>.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 7.47 | 8.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL127 | MEROPENEM | 4.0 | 1 | 8.00 |
| CHEMBL262777 | VANCOMYCIN | 4.0 | 1 | 7.40 |
| CHEMBL1730 | CEFOTAXIME | 4.0 | 1 | 7.00 |
| CHEMBL4460626 | — | — | 1 | - |
| CHEMBL106 | FLUCONAZOLE | 4.0 | 1 | - |
| CHEMBL267345 | AMPHOTERICIN B | 4.0 | 1 | - |
| CHEMBL8 | CIPROFLOXACIN | 4.0 | 1 | - |
| CHEMBL575 | METHICILLIN | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL127 | MEROPENEM | IC50 | = | 10.0 | nM | 8.00 |
| CHEMBL262777 | VANCOMYCIN | IC50 | = | 40.0 | nM | 7.40 |
| CHEMBL1730 | CEFOTAXIME | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL4460626 | — | IC50 | > | 30.0 | nM | - |
| CHEMBL106 | FLUCONAZOLE | IC50 | > | 300.0 | nM | - |
| CHEMBL267345 | AMPHOTERICIN B | IC50 | > | 100.0 | nM | - |
| CHEMBL8 | CIPROFLOXACIN | IC50 | < | 0.03 | nM | - |
| CHEMBL575 | METHICILLIN | IC50 | > | 300.0 | nM | - |